Description

(2S)-Pyrrolidine-2-Carboxylic Acid CAS NO 4607-28-7 is a high-purity, non-proteinogenic amino acid derivative characterized by its chiral pyrrolidine structure. This compound is a critical chiral building block and intermediate in organic synthesis, valued for its role in constructing complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of proline-based drugs, peptidomimetics, and protease inhibitors.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and organocatalysts in enantioselective synthesis.
• Agrochemical Research: Serves as a building block for developing novel, chiral active ingredients with specific biological activity.
• Peptide Chemistry: Incorporated into custom peptides and peptide analogs to modify structure, stability, and bioactivity.
• Biochemical Research: Utilized in metabolic studies and as a standard or reagent in analytical methodologies.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(2S)-Pyrrolidine-2-Carboxylic Acid
CAS No.	4607-28-7
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	(S)-(-)-Proline; L-Proline; (S)-Pyrrolidine-2-carboxylic acid; Proline, L-; (-)-Proline; (S)-2-Pyrrolidinecarboxylic Acid; L-Pyrrolidine-2-carboxylic Acid; (2S)-2-Carboxypyrrolidine
EINECS	225-006-0

Quality Control

Our (2S)-Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing specific results for purity, identity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.