Description

Eledoisin (6-11) CAS NO 4575-63-7 is a bioactive peptide fragment derived from the natural tachykinin peptide eledoisin. This specific hexapeptide sequence is a critical research tool for studying neurokinin receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D departments and academic research institutions focused on neuroscience, pharmacology, and drug discovery. The compound's defined structure allows for precise investigation into peptide-receptor binding and the development of novel therapeutic agents.

Application

• Neuroscience Research: Used as a selective ligand for studying Neurokinin B (NKB) and related tachykinin receptors in central and peripheral nervous system models.
• Pharmacological Assay Development: Serves as a reference standard and active component in high-throughput screening (HTS) assays for receptor agonist/antagonist activity.
• Drug Discovery & Medicinal Chemistry: Provides a core structure for the design, synthesis, and structure-activity relationship (SAR) studies of new neurokinin receptor modulators.
• Biochemical Studies: Employed in protein-protein interaction studies, signal transduction pathway analysis, and enzyme kinetics related to peptide metabolism.
• Academic & Institutional Research: A key reagent for university and government labs conducting fundamental research in peptide biology and neuropharmacology.

Basic Information

Product Name	Eledoisin (6-11)
CAS No.	4575-63-7
Molecular Formula	C34H51N9O9S
Molecular Weight	737.89 g/mol
Synonyms	Eledoisin fragment 6-11; H-Asp-Pro-Lys-Leu-Ala-Phe-OH; L-Aspartyl-L-prolyl-L-lysyl-L-leucyl-L-alanyl-L-phenylalanine; [Ala5, Phe6]-Eledoisin-(6-11); Neurokinin B receptor ligand fragment; Tachykinin peptide fragment; Eledoisin hexapeptide
EINECS	Contact for details

Quality Control

Our Eledoisin (6-11) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.