Description

H-Cys(Bzl)-Obzl Hcl is a protected cysteine derivative, specifically S-benzyl-L-cysteine benzyl ester hydrochloride, widely utilized as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over side-chain reactivity and stereochemistry during complex peptide assembly. It is a key intermediate for pharmaceutical R&D, particularly in the development of therapeutic peptides, APIs, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A fundamental building block for the controlled incorporation of cysteine residues in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and investigational new drugs targeting various diseases.
• Bioconjugation & Protein Engineering: Serves as a precursor for introducing thiol-reactive handles or protected thiol groups for site-specific labeling and protein modification.
• Biochemical Tool Development: Employed in creating enzyme substrates, inhibitors, and probes where a protected cysteine moiety is required.
• Academic & Industrial Research: A standard reagent in chemistry and biochemistry laboratories for studying peptide structure, function, and folding.

Basic Information

Product Name	H-Cys(Bzl)-Obzl Hcl
CAS No.	4561-11-9
Molecular Formula	C17H20ClNO2S
Molecular Weight	337.86 g/mol
Synonyms	S-Benzyl-L-cysteine benzyl ester hydrochloride; L-Cysteine, S-benzyl-, benzyl ester, hydrochloride; Benzyl S-benzyl-L-cysteinate hydrochloride; Cys(Bzl)-OBzl HCl; H-Cys(Bzl)-OBzl·HCl; (R)-2-Amino-3-(benzylthio)propanoic acid benzyl ester hydrochloride; N-Deprotected S-benzyl cysteine benzyl ester HCl; Bzl-Cys-OBzl HCl
EINECS	Contact for details

Quality Control

Our H-Cys(Bzl)-Obzl Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.