Description

Boc-Glycine is a crucial N-α-protected amino acid derivative, widely recognized as a fundamental building block in peptide synthesis. Its primary value lies in providing a temporary protective group for the amine functionality of glycine, preventing unwanted side reactions during the coupling of amino acid sequences. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity intermediates for the development of novel peptides and therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key starting material for the automated synthesis of custom peptides and peptide libraries.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Biochemical Research: Employed in enzymatic studies, substrate preparation, and as a standard in analytical method development.
• Combinatorial Chemistry: A vital component for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Material Science: Can be incorporated into peptide-based polymers and biomaterials for specialized applications.

Basic Information

Product Name	Boc-Glycine
CAS No.	4530-20-5
Molecular Formula	C7H13NO4
Molecular Weight	175.18 g/mol
Synonyms	N-(tert-Butoxycarbonyl)glycine; N-Boc-glycine; Boc-Gly-OH; (tert-Butoxycarbonyl)aminoacetic acid; 2-[(2-Methylpropan-2-yl)oxycarbonylamino]acetic acid; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-; BOC-Gly; N-tert-Butoxycarbonylglycine
EINECS	224-874-5

Quality Control

Our Boc-Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting or exceeding >98.5% purity by HPLC analysis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are kept sealed when not in use to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Melting Point	86 - 90 °C
Specific Rotation	-
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.