Description

2,3-Difluoroaniline is a versatile fluorinated aromatic amine building block essential for advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the fluorine substituents, enabling the development of high-performance materials and active compounds. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and pesticides, where fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic displays and organic light-emitting diodes due to its electronic properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Manufacturing: Serves as an intermediate for synthesizing novel fluorinated dyes and pigments with enhanced color fastness.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aromatic amines.

Basic Information

Product Name	2,3-Difluoroaniline
CAS No.	4519-40-8
Molecular Formula	C6H5F2N
Molecular Weight	129.11 g/mol
Synonyms	2,3-Difluorobenzenamine; 2,3-Difluorophenylamine; 1-Amino-2,3-difluorobenzene; Benzenamine, 2,3-difluoro-; 2,3-DFA; 2,3-Difluoroaniline (technical grade); 2,3-Difluoro-1-aminobenzene; 2,3-Difluoroaniline, 98+%
EINECS	Contact for details

Quality Control

Our 2,3-Difluoroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to confirm identity and purity while monitoring key impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to minimize oxidation. Keep away from strong acids, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Density (at 20°C)	~1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.