Description

Sodium Ketoisocaproate is the sodium salt of the branched-chain keto acid, α-ketoisocaproic acid. This compound serves as a critical biochemical intermediate and precursor in metabolic pathways, offering significant value in research and industrial synthesis. It is primarily utilized by the pharmaceutical, nutraceutical, and life science research sectors for applications in metabolic studies, cell culture media supplementation, and as a building block for more complex molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.
• Biochemical Research: Serves as a key substrate in metabolic pathway studies, particularly those involving branched-chain amino acid catabolism.
• Cell Culture & Fermentation: Acts as a component in specialized cell culture media and fermentation broths to support specific metabolic needs.
• Nutraceutical Precursor: Employed in the development of specialized nutritional supplements targeting metabolic health.
• Diagnostic Reagent Manufacturing: Used in the formulation of diagnostic kits and reagents for clinical biochemistry.
• Enzymology Studies: Functions as a substrate for enzyme activity assays, including those for dehydrogenases and transaminases.

Basic Information

Product Name	Sodium Ketoisocaproate
CAS No.	4502-00-5
Molecular Formula	C6H9NaO3
Molecular Weight	152.12 g/mol
Synonyms	Sodium α-Ketoisocaproate; Sodium 2-Oxo-4-methylpentanoate; 4-Methyl-2-oxopentanoic acid sodium salt; KIC sodium salt; α-Ketoisocaproic acid sodium salt; 2-Keto-4-methylvaleric acid sodium salt; 2-Oxoisocaproic acid sodium salt; L-Leucine keto acid sodium salt
EINECS	Contact for details

Quality Control

Our Sodium Ketoisocaproate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvent content. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (5% solution)	6.5 - 8.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.