Description

Angiotensin II, Human is a potent vasoconstrictor peptide hormone that plays a critical role in the renin-angiotensin system (RAS), regulating blood pressure and fluid balance. This high-purity peptide is essential for advanced pharmaceutical research and development, particularly in cardiovascular and renal disease studies. It is a key reagent for biochemical research, diagnostic assay development, and as a reference standard in quality control laboratories.

Application

• Pharmaceutical R&D: Critical reference standard and active ingredient in research for hypertension, heart failure, and kidney disease therapeutics.
• Biochemical Research: Used in receptor binding studies, signal transduction pathway analysis, and enzymatic activity assays related to the RAS.
• Diagnostic Manufacturing: Serves as a calibrator and control in immunoassay kits for measuring renin and angiotensin levels.
• Academic Research: Fundamental tool for physiological and pharmacological studies in university and institutional labs.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study vascular smooth muscle contraction and adrenal gland function.

Basic Information

Product Name	Angiotensin II, Human
CAS No.	4474-91-3
Molecular Formula	C50H71N13O12
Molecular Weight	1046.2 g/mol
Synonyms	Angiotensin II; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe; DRVYIHPF; All-Des-Asp1-Angiotensin I; Angiotensin II (1-8); Human Angiotensin II; Hypertensin; Angiotensinamide; [Asp1, Val5]-Angiotensin II
EINECS	Contact for details

Quality Control

Our Angiotensin II, Human is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmacopeial guidelines and cGMP principles for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.