Description

H-Leu-Leu-Gly-Oh is a synthetic tripeptide composed of two leucine residues and one glycine residue. This compound serves as a crucial building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by research institutions and manufacturers in the life sciences sector for developing novel therapeutic agents and biochemical tools. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D and production processes.

Application

• Pharmaceutical Intermediate: Key starting material or fragment in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate, inhibitor, or model compound in enzymatic studies and metabolic pathway investigations.
• Peptide Library Construction: A fundamental component for creating combinatorial peptide libraries used in drug discovery and high-throughput screening.
• Protease & Enzyme Studies: Employed to study the specificity and kinetics of proteolytic enzymes due to its specific amino acid sequence.
• Cell Culture & Media Supplement: May be used in specialized cell culture media as a nutrient or signaling molecule precursor.
• Cosmetic Peptide Synthesis: Potential intermediate for the production of bioactive peptides used in advanced skincare formulations.

Basic Information

Product Name	H-Leu-Leu-Gly-Oh
CAS No.	4464-36-2
Molecular Formula	C14H26N3O4
Molecular Weight	300.38 g/mol
Synonyms	L-Leucyl-L-leucylglycine; Leu-Leu-Gly; LLG; Glycine, L-leucyl-L-leucyl-; H-LLG-OH; N-(N-L-Leucyl-L-leucyl)glycine; Tripeptide LLG; 2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetic acid
EINECS	Contact for details

Quality Control

Our H-Leu-Leu-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.