Description

2-Methylene-β-Alanine is a specialized, high-purity amino acid derivative with a reactive methylene group. This compound is valued for its role as a versatile building block in organic synthesis and pharmaceutical research, enabling the creation of complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of β-amino acid-based drugs, peptidomimetics, and novel therapeutic agents.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators that incorporate β-alanine scaffolds.
• Bioconjugation & Linker Chemistry: The reactive methylene group facilitates its use as a spacer or linker in bioconjugation for antibody-drug conjugates (ADCs) and probe development.
• Fine Chemical Synthesis: Serves as a building block for synthesizing specialty chemicals, flavors, fragrances, and advanced polymers.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways involving β-alanine.
• Material Science: A monomer or modifier in the production of functional polymers and smart materials with tailored properties.

Basic Information

Product Name	2-Methylene-β-Alanine
CAS No.	4452-16-8
Molecular Formula	C4H7NO2
Molecular Weight	101.10 g/mol
Synonyms	3-Amino-2-methylenepropanoic acid; 2-Methylenebetaalanine; 2-Methylen-β-alanin; 2-Methylen-3-aminopropionic acid; β-Alanine, 2-methylene-; 2-Methylen-β-alanin [German]; 2-Methylen-β-alanine; NSC 163022
EINECS	Contact for details

Quality Control

Our 2-Methylene-β-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.