Description

2-Pyrimidinecarboxamide, N-Hydroxy- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor and intermediate in the development of pharmacologically active molecules, particularly those targeting enzymatic inhibition. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs. Its unique structure offers a versatile handle for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly enzyme inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various therapeutic targets.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and protein function.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents.
• Academic Research: Employed in universities and research institutes for methodological development in heterocyclic chemistry.
• Custom Synthesis: Used by fine chemical manufacturers for the contract synthesis of complex, high-value molecules.

Basic Information

Product Name	2-Pyrimidinecarboxamide, N-Hydroxy- (9Ci)
CAS No.	4425-55-2
Molecular Formula	C5H5N3O2
Molecular Weight	139.11 g/mol
Synonyms	N-Hydroxy-2-pyrimidinecarboxamide; N-Hydroxypyrimidine-2-carboxamide; 2-Pyrimidinecarbohydroxamic acid; Hydroxamic acid, 2-pyrimidinyl-; Pyrimidine-2-carbohydroxamic acid; 2-Carbamoylpyrimidine N-oxide; Isonicotinic acid, 4-hydroxy- (related); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarboxamide, N-Hydroxy- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We offer material suitable for research and development applications, with typical purity levels meeting the requirements of advanced synthetic chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.