Description

16β-(Acetyloxy)-3β-[(6-Deoxy-3-o-Methyl-α-L-Altropyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for developing targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel cardiovascular drugs and biochemical research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
• Biochemical Research: Used as a reference standard or active agent in studies investigating sodium-potassium ATPase inhibition and cardiac cell function.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with optimized efficacy and safety profiles.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.

Basic Information

Product Name	16β-(Acetyloxy)-3β-[(6-Deoxy-3-o-Methyl-α-L-Altropyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No.	4420-67-1
Molecular Formula	C30H44O9
Molecular Weight	548.67 g/mol
Synonyms	Acetyldigitoxin-α; 3''-O-Methylacetyldigitoxin; 3''-O-Methyl-α-acetyldigitoxin; 16β-Acetoxy-3β-[(6-deoxy-3-O-methyl-α-L-altropyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; Digitoxin, 16-acetate, 3''-methyl ether; 3''-O-Methyl-α-acetyldigitoxin; 16-Acetylgitoxin 3''-methyl ether
EINECS	Contact for details

Quality Control

Our 16β-(Acetyloxy)-3β-[(6-Deoxy-3-o-Methyl-α-L-Altropyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.