Description

α-Methylphenylalanine is a non-natural, chiral amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its unique structure, featuring a methyl group on the alpha carbon of the phenylalanine backbone, makes it a valuable building block for creating novel peptide mimetics and bioactive compounds. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of enzyme inhibitors, chiral catalysts, and specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly enzyme inhibitors and receptor modulators.
• Peptidomimetics Research: Serves as a critical building block for constructing peptide analogs with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in the synthesis of enantiomerically pure compounds for agrochemicals and fine chemicals.
• Biochemical Research: Used in studies investigating amino acid transport, metabolism, and incorporation into non-natural proteins or peptides.
• Material Science: Potential monomer for the synthesis of specialized polymers with unique optical or structural properties.

Basic Information

Product Name	α-Methylphenylalanine
CAS No.	4415-69-4
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	2-Amino-2-methyl-3-phenylpropanoic acid; (RS)-2-Amino-2-methyl-3-phenylpropionic acid; DL-α-Methylphenylalanine; (±)-α-Methylphenylalanine; 2-Methyl-2-aminophenylpropionic acid; α-Methyl-DL-phenylalanine; NSC 163080
EINECS	224-574-5

Quality Control

Our α-Methylphenylalanine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric purity (where applicable), and impurity profiles. We support customer-specific quality requirements and can provide material compliant with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.