Description

Propiophenone, 2-Amino-3-Fluoro-4-Hydroxy- (7Ci,8Ci) is a fluorinated amino-propiophenone derivative, a high-value intermediate characterized by its unique molecular scaffold. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the introduction of key functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals. The CAS number for this compound is 4394-59-6.

Application

This fluorinated intermediate is designed for sophisticated synthetic pathways, serving as a critical precursor in several high-value applications.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential substrate for studying structure-activity relationships (SAR) and introducing fluorine into complex molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-purity specialty chemicals for various industrial applications.

Basic Information

Product Name	Propiophenone, 2-Amino-3-Fluoro-4-Hydroxy- (7Ci,8Ci)
CAS No.	4394-59-6
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-Amino-3-fluoro-4-hydroxypropiophenone; 1-(2-Amino-3-fluoro-4-hydroxyphenyl)propan-1-one; 3-Fluoro-2-amino-4-hydroxypropiophenone; 4394-59-6; Propiophenone, 2-amino-3-fluoro-4-hydroxy-; 2-Amino-3-fluoro-4-hydroxy-1-phenylpropan-1-one
EINECS	Contact for details

Quality Control

Our Propiophenone, 2-Amino-3-Fluoro-4-Hydroxy- (7Ci,8Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.