Description

o-Methyl Threonine is a specialized, non-proteinogenic amino acid derivative of threonine. This compound matters as a crucial chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with high stereochemical purity. It is primarily needed by research institutions and pharmaceutical companies developing novel therapeutics, peptide mimetics, and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for antibiotics and metabolic drugs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce modified threonine residues, altering peptide stability and bioactivity.
• Biochemical Research: Serves as a substrate analog in enzymatic studies to investigate the mechanism and inhibition of threonine-metabolizing enzymes.
• Agrochemical Synthesis: An intermediate in the production of specialized, high-value crop protection agents and plant growth regulators.
• Ligand and Catalyst Development: Employed in the design of chiral ligands for asymmetric catalysis and metal complexes.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	o-Methyl Threonine
CAS No.	4385-90-4
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S,3S)-2-Amino-3-methoxybutanoic acid; (2S,3S)-3-Methoxy-2-aminobutanoic acid; O-Methyl-L-threonine; L-O-Methylthreonine; (2S,3S)-3-Methoxybutanoic acid, 2-amino-; 3-Methoxy-L-threonine; 2-Amino-3-methoxybutyric acid; allo-O-Methylthreonine
EINECS	Contact for details

Quality Control

Our o-Methyl Threonine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing lot-specific data for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.