Description

Cyclohexyl-Methanesulfonyl Chloride CAS NO 4352-30-1 is a versatile and reactive organosulfur compound primarily used as a key sulfonylation reagent and building block in advanced organic synthesis. Its value lies in its ability to introduce the cyclohexylmethanesulfonyl (CHMS) group, a valuable moiety for modifying molecular properties and creating novel chemical entities. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of potential drug candidates, particularly in creating sulfonamide derivatives with targeted biological activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the sulfonyl chloride group enables key structural modifications.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of specialty polymers with tailored surface properties or reactivity.
• Material Science Research: Employed in surface modification and the creation of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or other biomolecules, facilitating studies on protein function and interaction.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for fine chemical and custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Item	Details
Product Name	Cyclohexyl-Methanesulfonyl Chloride
CAS No.	4352-30-1
Molecular Formula	C8H15ClO2S
Molecular Weight	210.72 g/mol
Synonyms	Cyclohexylmethanesulfonyl chloride; Cyclohexylmethylsulfonyl chloride; (Cyclohexylmethyl)sulfonyl chloride; CHMS-Cl; Cyclohexanemethanesulfonyl chloride; Cyclohexylmethanesulphonyl chloride; Cyclohexylmethyl sulfone chloride; α-Cyclohexylmethanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclohexyl-Methanesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.