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3β-[(6-Deoxy-β-D-Allopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide CAS NO 4336-94-1


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CAS No.:4336-94-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-β-D-Allopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for developing targeted therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel cardiovascular drugs and biochemical research.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
  • Biochemical Research: Used as a reference standard or active agent in studies investigating heart muscle contractility and ion channel function.
  • Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with optimized efficacy and safety profiles.
  • Analytical Standard: Employed in quality control laboratories for HPLC, LC-MS, or NMR method development and calibration.
  • Academic Research: Utilized in university and institutional labs for pharmacological and toxicological investigations.

Basic Information

Product Name 3β-[(6-Deoxy-β-D-Allopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No. 4336-94-1
Molecular Formula C29H42O10
Molecular Weight 550.64 g/mol
Synonyms 19-Oxocymarin; 19-Oxocinobufagin 3-alloside; Cymarol 19-aldehyde; 3β-[(6-Deoxy-β-D-allopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β,14β-card-20(22)-enolide; 19-Oxo-cymarol; Strophanthidin 3-alloside 19-aldehyde; 3-Allosyl-19-oxo-strophanthidin
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Quality Control

Our 3β-[(6-Deoxy-β-D-Allopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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