Description

Oxytocin, Glu(4)- CAS NO 4314-67-4 is a synthetic analog of the neuropeptide hormone oxytocin, where the fourth amino acid residue is a glutamic acid. This specific modification is of significant interest for advanced biochemical and pharmacological research, offering a tool to study receptor binding and signal transduction mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroendocrinology, peptide chemistry, and drug discovery programs.

Application

• Biochemical Research: Used as a reference standard and probe in studies of oxytocin receptor (OTR) structure, function, and ligand interactions.
• Pharmacological Studies: Employed to investigate the effects of specific amino acid substitutions on peptide hormone activity, potency, and selectivity.
• Drug Discovery: Serves as a key intermediate or template in the design and synthesis of novel peptide-based therapeutics targeting the oxytocin pathway.
• Analytical Standard: Acts as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses for method development and validation.
• Neuroscience Research: Applied in vitro and in vivo models to explore the role of modified oxytocin analogs in social behavior, stress response, and other neurological functions.

Basic Information

Product Name	Oxytocin, Glu(4)- CAS NO 4314-67-4
CAS No.	4314-67-4
Molecular Formula	C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	[4-Glutamic acid]-Oxytocin; Glu4-Oxytocin; 4-Glu-Oxytocin; Oxytocin (Glu4 analog); 1-{(4R,7S,10S,13S,16S,19R)-19-Amino-13-benzyl-10-(2-carboxyethyl)-7-(carboxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}ethan-1-one; OXT (Glu4); Synthetic oxytocin analog
EINECS	Contact for details

Quality Control

Our Oxytocin, Glu(4)- is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.