Description

n-Formyl-L-Methionine is a chemically modified derivative of the essential amino acid L-Methionine, where a formyl group protects the amino terminus. This modification is critical for its role as a key intermediate in the biosynthesis of proteins and peptides, particularly in prokaryotic systems where it serves as the initiator amino acid. It is an essential raw material for researchers and manufacturers in the pharmaceutical and biotechnology sectors, enabling the study and production of novel therapeutic peptides and recombinant proteins.

Application

• Pharmaceutical Intermediate: Used in the synthesis and research of peptide-based drugs and antibiotics.
• Biochemical Research: Serves as a crucial reagent in molecular biology for studying protein biosynthesis, particularly initiation mechanisms.
• Cell Culture Media Component: Employed in specialized microbial fermentation and cell culture processes.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC and other chromatographic methods.
• Enzymology Studies: Applied in research involving methionyl-tRNA transformylase and other related enzymes.

Basic Information

Product Name	n-Formyl-L-Methionine
CAS No.	4309-82-4
Molecular Formula	C6H11NO3S
Molecular Weight	177.22 g/mol
Synonyms	Formylmethionine; N-Formylmethionine; L-Methionine, N-formyl-; N-Formyl-L-methionine; For-Met-OH; (S)-2-Amino-4-(methylthio)butanoic acid formyl derivative; Initiator methionine; fMet
EINECS	224-350-5

Quality Control

Our n-Formyl-L-Methionine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity (by HPLC), and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-30.0° to -34.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.