Description

H-Gly-Leu-Tyr-Oh CAS NO 4306-24-5 is a high-purity tripeptide derivative, specifically the C-terminal acid form of the Gly-Leu-Tyr sequence. This compound serves as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of peptide synthesis, proteomics, and medicinal chemistry who require reliable, well-characterized intermediates for drug discovery and diagnostic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, proteolysis research, and investigations into peptide structure-activity relationships (SAR).
• Proteomics & Diagnostics: Employed in the development of calibration standards for mass spectrometry and in the design of synthetic antigens for immunoassay development.
• Cosmeceutical R&D: Investigated for potential applications in bioactive cosmetic formulations targeting skin conditioning and anti-aging properties.
• Academic Research: A fundamental tool for university and institutional labs studying peptide chemistry, metabolism, and bio-conjugation techniques.

Basic Information

Product Name	H-Gly-Leu-Tyr-Oh
CAS No.	4306-24-5
Molecular Formula	C17H25N3O5
Molecular Weight	351.40 g/mol
Synonyms	Glycyl-L-leucyl-L-tyrosine; L-Tyrosine, glycyl-L-leucyl-; Gly-Leu-Tyr; GLY-LEU-TYR; H-Gly-Leu-Tyr-OH; Glycine-L-leucine-L-tyrosine; NSC 334905; Z-Gly-Leu-Tyr-OH (related protected form)
EINECS	Contact for details

Quality Control

Every batch of H-Gly-Leu-Tyr-Oh is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.