Description

L-Tryptophan Benzyl Ester is a protected derivative of the essential amino acid L-Tryptophan, where the carboxylic acid group is esterified with benzyl alcohol. This modification is crucial for its primary role as a key chiral building block and intermediate in the synthesis of complex peptides and pharmaceutical compounds. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, optically active intermediates for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) where the benzyl ester protecting group is required.
• Biochemical Research: Serves as a standard or reagent in studies involving tryptophan metabolism, protein engineering, and structural biology.
• Asymmetric Synthesis: Employed as a starting material for the preparation of non-natural amino acids and other complex chiral targets.
• Fine Chemical Production: An intermediate in the manufacture of specialty chemicals, agrochemicals, and advanced materials.

Basic Information

Product Name	L-Tryptophan Benzyl Ester
CAS No.	4299-69-8
Molecular Formula	C19H20N2O2
Molecular Weight	308.38 g/mol
Synonyms	H-Trp-OBzl; (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid benzyl ester; Benzyl L-tryptophanate; L-Tryptophan benzyl ester hydrochloride (salt form); Tryptophan benzyl ester; Boc-Trp-OBzl (protected form); Fmoc-Trp(Boc)-OBzl (protected form); Z-Trp-OBzl
EINECS	Contact for details

Quality Control

Our L-Tryptophan Benzyl Ester is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. We ensure compliance with relevant industry standards for fine chemical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.