Description

Dl-Threo-β-Hydroxyaspartic Acid is a non-proteinogenic amino acid derivative of aspartic acid, featuring a hydroxyl group on the β-carbon. This compound is a crucial chiral building block and biochemical tool in advanced research and synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications ranging from medicinal chemistry to the study of enzyme mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, especially for research involving aspartate aminotransferases and other enzymes that interact with aspartic acid analogs.
• Peptide Synthesis: Incorporated into synthetic peptides to introduce conformational constraints or to study structure-activity relationships due to its hydroxylated side chain.
• Agrochemical Development: Acts as a precursor in the synthesis of specialized amino acid-based herbicides or plant growth regulators.
• Neuroscience Research: Investigated for its potential role in modulating glutamate transporter function, relevant to studies on excitotoxicity and neuroprotection.
• Fine Chemical Synthesis: Employed as a versatile building block for the preparation of complex, high-value organic molecules in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	Dl-Threo-β-Hydroxyaspartic Acid
CAS No.	4294-45-5
Molecular Formula	C4H7NO5
Molecular Weight	149.10 g/mol
Synonyms	DL-threo-β-Hydroxyaspartic Acid; (±)-threo-3-Hydroxyaspartic Acid; 2-Amino-3-hydroxybutanedioic acid; HOAsp; Hydroxyaspartate; threo-β-Hydroxy-DL-aspartic Acid; 3-Hydroxyaspartic Acid; β-Hydroxyaspartate
EINECS	Contact for details

Quality Control

Our Dl-Threo-β-Hydroxyaspartic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy. We provide full traceability and a Certificate of Analysis (COA) with every shipment to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.