Description

Oxytocin, Des-Glynh2(9)- CAS NO 4294-07-9 is a synthetic peptide analog of the neurohypophysial hormone oxytocin, specifically lacking the C-terminal glycinamide residue. This modification is critical for research into the structure-activity relationships of oxytocin and its receptor binding mechanisms. It serves as a key intermediate and reference standard for pharmaceutical development and advanced biochemical studies. This high-purity compound is essential for researchers and manufacturers in neuroendocrinology, peptide chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a crucial reference standard and intermediate in the synthesis and study of oxytocin analogs and related peptide hormones.
• Neuroendocrine Studies: For investigating the biological activity, receptor binding affinity, and metabolic pathways of oxytocin-like peptides.
• Biochemical Assay Development: Used in the calibration and validation of analytical methods such as HPLC and mass spectrometry for peptide quantification.
• Academic Research: A vital tool in university and institutional labs for fundamental studies in physiology, behavior, and peptide pharmacology.
• Peptide Library Synthesis: Serves as a building block or template for creating focused libraries of peptide analogs for high-throughput screening.
• Quality Control: Employed as an impurity marker or system suitability standard in the quality control of oxytocin API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	Oxytocin, Des-Glynh2(9)- CAS NO 4294-07-9
CAS No.	4294-07-9
Molecular Formula	C₄₂H₆₆N₁₂O₁₂S₂
Molecular Weight	995.2 g/mol
Synonyms	Des-Glycinamide-oxytocin; [1-8]-Oxytocin; 1-8-Oxytocin; Des-Gly-NH₂⁹-oxytocin; Oxytocin (1-8); Oxytocin, 9-desglycinamide; Deamino-oxytocin, 9-desglycinamide; (2S)-N-[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-13-[(1H-imidazol-5-yl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicos-4-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2S)-2-aminobutanoyl]pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Oxytocin, Des-Glynh2(9)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) detailing all specifications and test results. The product is suitable for use as a pharmaceutical reference standard and is produced with traceability in mind, supporting research requiring the highest levels of accuracy and reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (IC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.