Description

4-(4-Fluoro-Phenyl)-Morpholine is a versatile heterocyclic building block featuring a morpholine ring linked to a fluorinated phenyl group. This compound matters as a key intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules. Its specific CAS number is 4280-40-4.

Application

• Pharmaceutical Intermediate: A critical synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of modern herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic and polar morpholine structure.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new organic reactions and creating compound libraries for high-throughput screening.
• Ligand and Catalyst Design: The morpholine nitrogen can act as a coordinating site in the design of novel ligands for catalytic systems.

Basic Information

Product Name	4-(4-Fluoro-Phenyl)-Morpholine
CAS No.	4280-40-4
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	4-(4-Fluorophenyl)morpholine; 4-(p-Fluorophenyl)morpholine; N-(4-Fluorophenyl)morpholine; 4-Fluorophenylmorpholine; Morpholine, 4-(4-fluorophenyl)-; 4280-40-4; p-Fluorophenylmorpholine
EINECS	Contact for details

Quality Control

Our 4-(4-Fluoro-Phenyl)-Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.