Description

3-Amino-4-Mercaptobenzotrifluoride Hydrochloride is a high-value trifluoromethylated aromatic building block, essential for introducing both amino and thiol functionalities into complex molecular architectures. Its unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) with enhanced properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the trifluoromethyl group.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group improves metabolic stability and bioavailability.
• Ligand for Catalysis: Serves as a versatile building block for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the research and production of advanced polymers, liquid crystals, and organic electronic materials requiring specific functional group integration.
• Chemical Research: A valuable reagent for academic and industrial R&D in organic synthesis, medicinal chemistry, and fluorochemistry studies.

Basic Information

Product Name	3-Amino-4-Mercaptobenzotrifluoride Hydrochloride
CAS No.	4274-38-8
Molecular Formula	C7H5F3N2S • HCl
Molecular Weight	242.64 g/mol
Synonyms	3-Amino-4-mercaptobenzotrifluoride HCl; 2-Amino-6-(trifluoromethyl)benzenethiol hydrochloride; 4-Mercapto-3-aminobenzotrifluoride hydrochloride; 3-Amino-α,α,α-trifluoro-4-mercaptotoluene hydrochloride; Benzenethiol, 2-amino-6-(trifluoromethyl)-, hydrochloride; 2-Amino-α,α,α-trifluoro-6-mercaptotoluene hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Mercaptobenzotrifluoride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.