Description

6-Bromouracil is a halogenated pyrimidine derivative, a key building block in organic synthesis and biochemical research. This compound is valued for its ability to act as a thymine analog, making it a crucial tool for studying mutagenesis and nucleic acid biochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside synthesis, molecular biology, and the development of novel therapeutic agents.

Application

• Nucleoside & Nucleotide Synthesis: A vital precursor in the chemical synthesis of modified nucleosides and nucleotides for pharmaceutical research.
• Biochemical Research: Used as a mutagenic base analog in studies of DNA replication, repair mechanisms, and genetic mutations.
• Antiviral/Anticancer Agent Development: Serves as a scaffold or intermediate in the research and development of potential antiviral and anticancer prodrugs.
• Organic Synthesis Intermediate: Employed in various organic transformations to introduce the bromouracil moiety into more complex molecular architectures.
• Academic & Industrial R&D: Essential for universities, contract research organizations (CROs), and biotech companies conducting fundamental life science research.

Basic Information

Product Name	6-Bromouracil
CAS No.	4269-93-6
Molecular Formula	C4H3BrN2O2
Molecular Weight	190.98 g/mol
Synonyms	5-Bromouracil; 5-Bromo-2,4(1H,3H)-pyrimidinedione; 5-BU; 5-Bromopyrimidine-2,4(1H,3H)-dione; Bromouracil; 6-Bromo-1H-pyrimidine-2,4-dione; NSC 38297
EINECS	224-246-8

Quality Control

Our 6-Bromouracil is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards expected by the pharmaceutical and biotechnology research sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	293°C - 298°C (dec.)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.