Description

3,4-Dihydroxyphenylpyruvic Acid is a key intermediate in the biosynthesis of aromatic amino acids and related metabolites. This compound matters for its role as a versatile building block in pharmaceutical research and fine chemical synthesis. It is needed by manufacturers and R&D teams in the pharmaceutical, biotechnology, and life science sectors for developing active pharmaceutical ingredients (APIs), enzyme inhibitors, and biochemical research tools.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of L-DOPA (Levodopa) and other catecholamine-based drugs for treating Parkinson's disease.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving tyrosine metabolism, phenylalanine hydroxylase, and related pathways.
• Fine Chemical Synthesis: Serves as a building block for synthesizing complex organic molecules, natural product analogs, and specialty chemicals.
• Metabolite Analysis: Employed as a reference standard in analytical methods (HPLC, LC-MS) for quantifying metabolic intermediates in clinical and research settings.
• Enzyme Inhibitor Development: Investigated for its potential in creating inhibitors for enzymes like 4-hydroxyphenylpyruvate dioxygenase (HPPD), relevant to herbicide and therapeutic research.
• Nutritional & Cosmetic Research: Explored for its antioxidant properties and potential applications in nutraceutical and cosmeceutical formulations.

Basic Information

Product Name	3,4-Dihydroxyphenylpyruvic Acid
CAS No.	4228-66-4
Molecular Formula	C9H8O5
Molecular Weight	196.16 g/mol
Synonyms	3,4-DHPPA; 2-Oxo-3-(3,4-dihydroxyphenyl)propanoic Acid; (3,4-Dihydroxyphenyl)pyruvic Acid; 3-(3,4-Dihydroxyphenyl)-2-oxopropanoic Acid; 3,4-Dihydroxybenzene pyruvic acid; 3,4-Dihydroxy-α-oxohydrocinnamic Acid
EINECS	224-191-7

Quality Control

Our 3,4-Dihydroxyphenylpyruvic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), identification (IR), and impurity profiles are provided and available upon request. We adhere to cGMP principles for pharmaceutical-grade material where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.