Description

n-Methyl-L-Aspartic Acid is a high-purity, non-proteinogenic amino acid derivative of L-aspartic acid. This compound is a critical chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from peptide synthesis to the development of enzyme inhibitors and neurological research compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used as a modified amino acid residue in the solid-phase and solution-phase synthesis of specialized peptides and peptidomimetics.
• Biochemical Research: Employed in enzymatic studies and as a precursor for compounds that interact with glutamate receptors and transporters in neurological research.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex organic molecules with specific stereochemical configurations.
• Agrochemical Development: Potential use in the synthesis of advanced, targeted agrochemicals and plant growth regulators.

Basic Information

Product Name	n-Methyl-L-Aspartic Acid
CAS No.	4226-18-0
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	(2S)-2-(Methylamino)butanedioic acid; L-Aspartic acid, N-methyl-; Methylaspartic acid; N-Methyl-L-aspartate precursor; NMDA precursor; 2-Methylaminosuccinic acid; (S)-2-(Methylamino)succinic acid
EINECS	224-178-3

Quality Control

Our n-Methyl-L-Aspartic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting standards for research and production use. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.