Description

Framycetin Sulphate is an aminoglycoside antibiotic salt, widely recognized for its potent bactericidal activity against a broad spectrum of Gram-negative and some Gram-positive bacteria. Its primary value lies in its effectiveness as a topical agent, offering a reliable solution for preventing and treating superficial infections. This makes it a critical raw material for manufacturers in the pharmaceutical and veterinary sectors, particularly for formulating ointments, creams, and eye/ear drops where localized, non-systemic antibiotic action is required.

Application

• Pharmaceutical Formulations: Primary use in topical antibiotic creams, ointments, and powders for skin infections.
• Ophthalmic Preparations: Key ingredient in eye drops and ointments for treating bacterial conjunctivitis and other eye infections.
• Veterinary Medicine: Used in topical preparations for treating bacterial infections in animals.
• Wound Care Products: Incorporated into medicated dressings and gels to prevent infection in minor cuts and burns.
• Nasal Sprays/Ointments: Applied in formulations aimed at treating or preventing nasal carriage of susceptible bacteria.
• Research & Development: Serves as a reference standard and active component in microbiological and pharmacological research.

Basic Information

Product Name	Framycetin Sulphate
CAS No.	4146-30-9
Molecular Formula	C23H46N6O13 · xH2SO4
Molecular Weight	615.65 g/mol (for Framycetin base)
Synonyms	Framycetin Sulfate; Soframycin; Framycein Sulphate; Antibiotic FRM; Deoxykanamycin B Sulfate; Neomycin B Sulfate; 2-Deoxystreptamine, 4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-6-O-(6-amino-6-deoxy-α-D-glucopyranosyl)-, sulfate (salt); Framycetinum
EINECS	223-981-7

Quality Control

Our Framycetin Sulphate is produced and tested under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch is subjected to comprehensive analytical testing, including identification, potency (assay), purity, and specific tests for related substances and residual solvents. Certificates of Analysis (COA) documenting compliance with relevant specifications, including in-house pharmacopeial standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
pH (10% solution)	5.0 - 7.5
Water (Karl Fischer)	≤ 8.0 %
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Sulfate Content (Titration)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Microbial Enumeration	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.