Description

4-{[(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Acetyl]Amino}-2-Hydroxybenzoic Acid is a high-purity, non-nucleoside heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers need this material for creating complex molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel uracil and pyrimidine-based drug candidates, including potential antiviral and anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage its heterocyclic core structure.
• Biochemical Probe Synthesis: Serves as a precursor for creating labeled compounds or molecular probes used in biochemical and pharmacological studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce functionalized benzoic acid and dihydropyrimidinone moieties into target molecules.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with specific thermal or optical properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-{[(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Acetyl]Amino}-2-Hydroxybenzoic Acid
CAS No.	4116-42-1
Molecular Formula	C₁₃H₁₁N₃O₆
Molecular Weight	305.24 g/mol
Synonyms	1-(2-Carboxy-4-hydroxyphenylcarbamoylmethyl)uracil; 4-[(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetamido]salicylic acid; N-[4-Carboxy-2-hydroxyphenyl]-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide; Uracil-1-ylacetamidosalicylic Acid; 4-[(2,4-Dioxopyrimidin-1(2H)-yl)acetamido]-2-hydroxybenzoic acid; 1-Carboxymethyluracil-4-aminosalicylic Acid Adduct; 4116-42-1; Uracil-salicylic acid conjugate
EINECS	Contact for details

Quality Control

Our 4-{[(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Acetyl]Amino}-2-Hydroxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets exacting R&D and pilot-scale production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.