Description

Acth (5-10) CAS NO 4086-29-7 is a synthetic peptide fragment of adrenocorticotropic hormone, specifically comprising amino acid residues 5 through 10. This compound is a critical research tool for studying the structure-activity relationships of ACTH and its role in the hypothalamic-pituitary-adrenal axis. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on endocrinology, peptide chemistry, and neurobiology.

Application

• Biomedical Research: Used as a reference standard and active probe in studies investigating ACTH receptor binding, steroidogenesis, and melanocortin system signaling.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the design and synthesis of novel peptide-based therapeutics targeting metabolic and inflammatory disorders.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and components for immunoassay kits measuring ACTH-related pathways.
• Academic Studies: Facilitates fundamental research in endocrinology, neuropeptide function, and the biochemical mechanisms of stress response.
• Peptide Library Synthesis: Acts as a building block or template for creating focused libraries to screen for biological activity and optimize peptide sequences.

Basic Information

Product Name	Acth (5-10)
CAS No.	4086-29-7
Molecular Formula	C34H50N10O9
Molecular Weight	742.82 g/mol
Synonyms	ACTH (5-10); Adrenocorticotropic Hormone (5-10) fragment; H-Met-Glu-His-Phe-Arg-Trp-OH; Corticotropin (5-10); Melanocyte-Stimulating Hormone release-inhibiting factor; MSH release-inhibiting factor; MIF-1 (related); Acethropan (5-10)
EINECS	Contact for details

Quality Control

Our Acth (5-10) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with detailed results for traceability and compliance. Our standards align with general requirements for research-grade peptides, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.