Description

D-3-Hydroxykynurenine is a key intermediate metabolite in the tryptophan degradation pathway, specifically within the kynurenine pathway. This compound is of significant interest for its role in biochemical research and its potential as a reference standard or building block in pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and nutraceutical industries. Our supply of D-3-Hydroxykynurenine CAS NO 4043-91-8 is characterized by high purity and reliable consistency to meet rigorous application demands.

Application

• Biochemical Research: Critical intermediate for studying the kynurenine pathway, neurobiology, immunology, and oxidative stress mechanisms.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery and development.
• Metabolite Analysis: Essential standard for quantitative analysis (e.g., LC-MS, HPLC) in metabolomics studies and clinical research related to tryptophan metabolism.
• Enzyme Substrate: Employed as a substrate for enzymes like kynureninase in enzymatic assays and inhibitor screening.
• Precursor Synthesis: Serves as a chiral building block or precursor for the synthesis of more complex molecules in medicinal chemistry.
• Nutritional & Cosmetic Research: Investigated for its potential role in skin health and its interactions with UV light, relevant to cosmetic science.

Basic Information

Item	Details
Product Name	D-3-Hydroxykynurenine
CAS No.	4043-91-8
Molecular Formula	C10H12N2O5
Molecular Weight	240.21 g/mol
Synonyms	(R)-3-Hydroxykynurenine; D-(-)-3-Hydroxykynurenine; (R)-2-Amino-4-(3-hydroxyanthraniloyl)butyric acid; 3-Hydroxy-D-kynurenine; (2R)-2-Amino-4-[(3-hydroxy-2-aminophenyl)carbonyl]butanoic acid; D-3-HK; HKYN (D-form)
EINECS	Contact for details

Quality Control

Our D-3-Hydroxykynurenine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.