Description

Nitroxoline is a synthetic antimicrobial agent belonging to the hydroxyquinoline chemical class. This compound is valued for its specific bacteriostatic and bactericidal properties against a range of microorganisms. It is primarily utilized in the pharmaceutical industry as an active pharmaceutical ingredient (API) for the formulation of urinary antiseptic medications. Nitroxoline CAS NO 4008-48-4 offers a targeted solution for manufacturers requiring a well-characterized antimicrobial component.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of urinary tract infections (UTIs).
• Antimicrobial Research: Serves as a reference standard or key intermediate in microbiological and pharmacological research studies.
• Veterinary Medicine: Potential application in veterinary pharmaceutical formulations for treating bacterial infections in animals.
• Chemical Synthesis: Used as a building block or intermediate in the synthesis of more complex quinoline-based derivatives.

Basic Information

Product Name	Nitroxoline
CAS No.	4008-48-4
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	5-Nitro-8-quinolinol; 8-Hydroxy-5-nitroquinoline; 5-Nitro-8-hydroxyquinoline; Nitroxolin; Nibiol; Uronorm; 5-Nitroquinolin-8-ol; 5-Nitro-8-quinolol
EINECS	223-664-1

Quality Control

Our Nitroxoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and the absence of specified impurities. We can support compliance with ICH guidelines and relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to yellow-brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.