Description

2-Bromo-4-Fluorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a valuable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo-fluoro-phenol moiety contributes to biological activity.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed as a functional monomer or cross-linking agent to impart specific properties like flame retardancy or chemical resistance to polymers.
• Chemical Research & Development: Serves as a standard reagent in academic and industrial R&D labs for method development and exploring new reaction pathways.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and pigments, where halogen atoms are crucial for color fastness and stability.

Basic Information

Product Name	2-Bromo-4-Fluorophenol
CAS No.	496-69-5
Molecular Formula	C6H4BrFO
Molecular Weight	191.00 g/mol
Synonyms	4-Fluoro-2-bromophenol; 2-Bromo-4-fluorophenol; 1-Bromo-2-fluoro-4-hydroxybenzene; Phenol, 2-bromo-4-fluoro-; o-Bromo-p-fluorophenol; 2-Bromo-4-fluoro-1-hydroxybenzene; 4-Fluoro-2-bromo-1-hydroxybenzene; 2-Br-4-F-PhOH
EINECS	207-831-7

Quality Control

Our 2-Bromo-4-Fluorophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.