Description

Glycocholic Acid is a conjugated bile acid formed from the amide linkage of cholic acid with the amino acid glycine. This compound plays a crucial role in the emulsification and absorption of dietary fats and fat-soluble vitamins in the intestine. It serves as a vital biochemical reagent and reference standard in pharmaceutical research and diagnostic applications. Key industries that utilize this product include pharmaceutical development, life science research, and the manufacturing of diagnostic kits.

Application

• Pharmaceutical Intermediate: Used in the synthesis of more complex bile acid derivatives and active pharmaceutical ingredients (APIs).
• Biochemical Research: Acts as a critical reference standard and reagent in studies of lipid metabolism, hepatobiliary function, and intestinal absorption.
• Diagnostic Manufacturing: Employed in the production of calibration standards and reagents for clinical diagnostic tests measuring liver function and bile acid profiles.
• Cell Culture & Microbiology: Utilized as a supplement in certain specialized cell culture media and in studies of microbial transformation of bile acids.
• Analytical Chemistry: Serves as a high-purity standard for HPLC, LC-MS, and other chromatographic methods in quality control and research laboratories.

Basic Information

Product Name	Glycocholic Acid
CAS No.	475-31-0
Molecular Formula	C₂₆H₄₃NO₆
Molecular Weight	465.62 g/mol
Synonyms	Glycocholic Acid; N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]glycine; Cholylglycine; Glycocholate; N-Choloylglycine; 3α,7α,12α-Trihydroxy-5β-cholan-24-oylglycine; Glycine-conjugated cholic acid
EINECS	207-481-8

Quality Control

Our Glycocholic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), assay (HPLC), and tests for related substances and residual solvents, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.