Description

Methitural CAS NO 467-43-6 is a thiobarbiturate derivative, a class of compounds historically significant in pharmaceutical research and development. This chemical is valued for its specific structural framework, which serves as a critical intermediate or reference standard in the synthesis and analytical profiling of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, neuroscience studies, and the development of central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research-scale synthesis of barbiturate analogs and related CNS-active compounds.
• Reference Standard: Used in analytical laboratories as a high-purity standard for method development, validation, and quality control testing via techniques like HPLC and GC.
• Biochemical Research: Employed in neuroscience and pharmacological studies to investigate the structure-activity relationships (SAR) of thiobarbiturates and their interactions with biological targets.
• Chemical Synthesis: Acts as a specialized precursor for synthesizing novel heterocyclic compounds in academic and industrial R&D settings.

Basic Information

Product Name	Methitural
CAS No.	467-43-6
Molecular Formula	C9H14N2O2S
Molecular Weight	214.28 g/mol
Synonyms	5-(1-Methylbutyl)-5-(2-propen-1-yl)-2-thiobarbituric acid; Methituralum; Thiogenal; NSC 526063; 5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid; 2-Thiobarbituric acid, 5-allyl-5-(1-methylbutyl)-; Methitural (INN)
EINECS	Contact for details

Quality Control

Our Methitural is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.