Description

Thialbarbital CAS NO 467-36-7 is a thiobarbiturate derivative, a class of compounds historically significant in medicinal chemistry for their central nervous system depressant properties. Its precise chemical structure makes it a valuable reference standard and a key intermediate in pharmaceutical research and development. This compound is primarily utilized by research institutions, analytical laboratories, and chemical manufacturers focused on neuropharmacology, forensic analysis, and the synthesis of specialized barbiturate analogs.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified material for analytical method development, validation, and quality control testing in laboratories.
• Biochemical Research: Serves as a tool compound in neuroscience and pharmacology studies to investigate the mechanism of action of barbiturates and related sedative-hypnotic agents.
• Chemical Synthesis Intermediate: Acts as a crucial building block for the research-scale synthesis of novel thiobarbiturate derivatives and analogs with potential biological activity.
• Forensic Analysis: Employed as an analytical standard for the identification and quantification of barbiturates in forensic toxicology and regulatory compliance testing.
• Academic Research: Used in university and institutional labs for educational purposes and advanced studies in medicinal chemistry and drug design.

Basic Information

Product Name	Thialbarbital
CAS No.	467-36-7
Molecular Formula	C₉H₁₂N₂O₂S
Molecular Weight	212.27 g/mol
Synonyms	5-Allyl-5-(2-cyclohexen-1-yl)-2-thiobarbituric acid; Thialbarbitone; Kemithal; Thiobarbital; 5-Allyl-5-(cyclohex-2-en-1-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione; NSC 33617; BRN 0207502
EINECS	207-401-5

Quality Control

Our Thialbarbital is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications. We support research and industrial applications requiring materials that meet stringent quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.