Description

Proscillaridin A CAS NO 466-06-8 is a potent cardiac glycoside derived from plants of the genus *Scilla*. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of cardiac pharmacology and drug discovery. It serves as an essential analytical standard for quality control in the production of related pharmaceutical intermediates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Cardiac Drug Research: Key biochemical tool for in-vitro and in-vivo studies targeting sodium-potassium ATPase activity and heart failure mechanisms.
• Academic & Contract Research: Used in university and CRO laboratories for pharmacological screening and mechanistic studies of cardiac glycosides.
• Impurity Profiling: Serves as a marker compound for the identification and quantification of related substances in bulk drug substances and finished dosage forms.
• Metabolite Studies: Employed in ADME (Absorption, Distribution, Metabolism, and Excretion) research to understand the metabolic pathways of similar therapeutic agents.

Basic Information

Product Name	Proscillaridin A
CAS No.	466-06-8
Molecular Formula	C30H42O8
Molecular Weight	530.65 g/mol
Synonyms	Proscillaridin; Proscillaridine A; 3β-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-19-oxo-5β,14β-bufa-20,22-dienolide; Transvaalin; Caradrin; Talusin
EINECS	Contact for details

Quality Control

Our Proscillaridin A is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical reference standards. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.