Description

(3Alpha,5Beta,12Beta)-3,12,14-Trihydroxycard-20(22)-Enolide is a high-purity steroidal lactone compound, also known as a cardenolide derivative. This compound is valued for its specific structural configuration, which is critical for advanced pharmaceutical research and development. It serves as a key intermediate or reference standard for researchers and manufacturers in the life sciences sector, particularly those developing or analyzing cardiac glycosides and related therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of specialized cardiac-active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related drug substances.
• Biochemical Research: Employed in academic and industrial research to study the structure-activity relationships (SAR) of cardenolides and their biological mechanisms.
• Active Pharmaceutical Ingredient (API) Development: Investigated for potential use in the development of new therapeutic agents targeting specific physiological pathways.

Basic Information

Product Name	(3Alpha,5Beta,12Beta)-3,12,14-Trihydroxycard-20(22)-Enolide
CAS No.	465-14-5
Molecular Formula	C₂₃H₃₄O₆
Molecular Weight	406.52 g/mol
Synonyms	3β,12β,14-Trihydroxy-5β-card-20(22)-enolide; 3β,12β,14-Trihydroxy-5β,14β-card-20(22)-enolide; 3,12,14-Trihydroxycard-20(22)-enolide; Cardenolide derivative; 3,12,14-Trihydroxycardenolide; 5β,14β-Cardenolide-3β,12β,14-triol 20(22)-enolide
EINECS	Contact for details

Quality Control

Our (3Alpha,5Beta,12Beta)-3,12,14-Trihydroxycard-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and mass spectrometry. Specifications can be aligned with research-grade or pharmaceutical intermediate standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.