Description

4-Fluorobutyric Acid is a versatile fluorinated carboxylic acid building block essential for advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom and a reactive carboxyl group, enabling the construction of complex molecules with modified properties. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential CNS agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & Material Science: Serves as a precursor for fluorinated monomers and polymers, contributing to the development of specialty materials with unique dielectric and surface properties.
• Organic Synthesis Building Block: Employed in peptide modification, linker chemistry, and the preparation of more complex fluorinated carboxylic acids and esters.
• Biochemical Research: Utilized as a probe or substrate in metabolic studies and enzyme research due to its fluorine label.

Basic Information

Product Name	4-Fluorobutyric Acid
CAS No.	462-23-7
Molecular Formula	C4H7FO2
Molecular Weight	106.10 g/mol
Synonyms	4-Fluorobutanoic Acid; γ-Fluorobutyric Acid; Butanoic acid, 4-fluoro-; NSC 60529; 4-Fluorobuttersäure (German); Acide 4-fluorobutyrique (French); 4-Fluorobutaanzuur (Dutch)
EINECS	207-324-4

Quality Control

Our 4-Fluorobutyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.