Description

Homocystine CAS NO 462-10-2 is a sulfur-containing amino acid dimer, formed by the oxidation of two homocysteine molecules. It serves as a critical reference standard and biochemical reagent for research into metabolic disorders, particularly homocystinuria and cardiovascular disease risk assessment. This high-purity compound is essential for pharmaceutical R&D, clinical diagnostics, and advanced life science applications where precise quantification and quality are paramount.

Application

• Biochemical Research & Reference Standard: Primary standard for calibrating analytical methods (HPLC, LC-MS) used in homocysteine and related metabolite quantification.
• Clinical Diagnostics: Key component in the development and validation of diagnostic kits and assays for detecting homocystinuria and monitoring plasma homocysteine levels.
• Pharmaceutical Development: Used as an intermediate or reference material in metabolic pathway studies and drug discovery programs targeting sulfur amino acid metabolism.
• Nutritional Science: Employed in studies investigating vitamin B12, B6, and folate deficiencies and their impact on homocysteine metabolism.
• Cell Culture & Microbiology: Utilized in defined media for studying the growth requirements of certain microorganisms and cell lines.

Basic Information

Product Name	Homocystine
CAS No.	462-10-2
Molecular Formula	C8H16N2O4S2
Molecular Weight	268.36 g/mol
Synonyms	L-Homocystine; (R,R)-2,2'-Diamino-4,4'-dithiodibutyric Acid; Dicysteine Homolog; 4,4'-Dithiobis(2-aminobutanoic Acid); Hcy2; DL-Homocystine; Homocysteine Dimer; 2-Amino-4-[(2-amino-2-carboxyethyl)dithio]butyric Acid
EINECS	207-313-3

Quality Control

Our Homocystine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We adhere to relevant industry guidelines to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure containers are sealed immediately after use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.