Description

4-Fluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its primary value lies in the reactive benzyl alcohol group and the electron-withdrawing fluorine substituent, which make it a key intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated benzyl motifs into their products.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorobenzyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter physical properties such as solubility, thermal stability, and chemical resistance.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol function can be used to protect other functional groups during multi-step synthetic sequences.

Basic Information

Product Name	4-Fluorobenzyl Alcohol
CAS No.	459-56-3
Molecular Formula	C7H7FO
Molecular Weight	126.13 g/mol
Synonyms	p-Fluorobenzyl Alcohol; (4-Fluorophenyl)methanol; 4-Fluorobenzenemethanol; α-Hydroxy-4-fluorotoluene; 1-(Hydroxymethyl)-4-fluorobenzene; 4-Fluorobenzylalcohol; p-Fluorobenzylalcohol; 4-FBA
EINECS	207-306-5

Quality Control

Our 4-Fluorobenzyl Alcohol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.