Description

1-Fluoro-4-Formamidobenzene is a versatile aromatic fluorine-containing building block with a formamide functional group. This compound is highly valued in organic synthesis for its dual reactivity, serving as a precursor for various heterocyclic and pharmaceutical intermediates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine and amide functionalities into polymer backbones to alter material properties.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to construct complex molecules.
• Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	1-Fluoro-4-Formamidobenzene
CAS No.	459-25-6
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	4-Fluoroformanilide; p-Fluoroformanilide; N-(4-Fluorophenyl)formamide; 4-Fluorophenylformamide; Formanilide, 4'-fluoro-; 1-Fluoro-4-formylaminobenzene; 4-Fluoro-N-formylaniline; 459-25-6
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-Formamidobenzene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.