Description

4-Fluorophenethylamine Hydrochloride is a high-purity organic salt of significant synthetic utility. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly for the construction of complex pharmaceutical intermediates and active ingredients. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce fluorinated phenethylamine motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides that benefit from the fluorinated aromatic structure.
• Chemical Research & Development: A fundamental building block for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies and lead optimization.
• Fluorinated Compound Library Synthesis: Critical for creating diverse screening libraries in drug discovery, leveraging the unique properties of fluorine atoms.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced materials.

Basic Information

Product Name	4-Fluorophenethylamine Hydrochloride
CAS No.	459-19-8
Molecular Formula	C8H10FN • HCl
Molecular Weight	175.63 g/mol (Free base: 139.17 g/mol)
Synonyms	2-(4-Fluorophenyl)ethanamine Hydrochloride; 4-Fluorophenylethylamine HCl; 4-Fluoro-β-phenethylamine Hydrochloride; 1-(4-Fluorophenyl)-2-aminoethane Hydrochloride; p-Fluorophenethylamine Hydrochloride; 4-F-PEA HCl; 4-Fluoro-PEA HCl; 4-Fluorobenzeneethanamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Fluorophenethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.