Description

n-(4-Chloro-3,5-Difluorophenyl)Acetamide is a high-purity, halogenated acetamide derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro and difluoro substitutions on the phenyl ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of its halogenated aromatic system.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals, where the introduction of fluorine atoms can modify thermal stability and optical properties.
• Organic Synthesis Building Block: A versatile reagent for cross-coupling reactions, amide bond formations, and further functionalization to create diverse chemical libraries for screening.

Basic Information

Product Name	n-(4-Chloro-3,5-Difluorophenyl)Acetamide
CAS No.	457-30-7
Molecular Formula	C8H6ClF2NO
Molecular Weight	205.59 g/mol
Synonyms	N-Acetyl-4-chloro-3,5-difluoroaniline; 4-Chloro-3,5-difluoroacetanilide; 2-Chloro-4,6-difluoroacetamide; Acetamide, N-(4-chloro-3,5-difluorophenyl)-; 457-30-7; 4-Chloro-3,5-difluoro-N-phenylacetamide; N-(4-Chloro-3,5-difluorophenyl)acetamide
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-3,5-Difluorophenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global B2B clients. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	148°C - 152°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.