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3-Fluorobenzyl Alcohol CAS NO 456-47-3
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CAS No.:456-47-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Fluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine substituent, which can dramatically alter the physical, chemical, and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key intermediate for creating novel active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates where the fluorine atom enhances metabolic stability and bioavailability.
- Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the introduction of fluorine can improve efficacy and environmental profile.
- Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
- Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to modify characteristics such as solvent resistance, thermal stability, and surface energy.
- Cross-coupling Reactions: Acts as a benzyl alcohol precursor in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
- Protecting Group Chemistry: Utilized in synthetic organic chemistry as a protected form of a benzyl group that can be selectively removed under specific conditions.
Basic Information
| Product Name | 3-Fluorobenzyl Alcohol |
| CAS No. | 456-47-3 |
| Molecular Formula | C7H7FO |
| Molecular Weight | 126.13 g/mol |
| Synonyms | (3-Fluorophenyl)methanol; m-Fluorobenzyl Alcohol; 3-Fluorobenzenemethanol; α-Hydroxymethyl-3-fluorobenzene; 1-(Hydroxymethyl)-3-fluorobenzene; 3-Fluorobenzylalcohol; m-Fluorobenzylalcohol; 3-FBA |
| EINECS | Contact for details |
Quality Control
Our 3-Fluorobenzyl Alcohol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to minimize exposure to moisture and air.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Assay (GC/HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Related Substances (GC/HPLC) | Total impurities ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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