Description

4-(Trifluoromethyl)Benzaldehyde is a high-purity aromatic aldehyde building block distinguished by its reactive formyl group and electron-withdrawing trifluoromethyl substituent. This compound is essential for synthesizing advanced intermediates where the introduction of fluorine atoms and aldehyde functionality is required, offering enhanced lipophilicity and metabolic stability to final products. It is a critical raw material for research and production in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used to manufacture advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for producing specialized dyes and pigments with unique color fastness and stability properties.
• Polymer & Resin Modifiers: Incorporated into polymer chains to alter physical properties such as chemical resistance, thermal stability, and surface characteristics.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating complex biaryl structures.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex molecules, including ligands for catalysis.

Basic Information

Product Name	4-(Trifluoromethyl)Benzaldehyde
CAS No.	455-19-6
Molecular Formula	C8H5F3O
Molecular Weight	174.12 g/mol
Synonyms	alpha,alpha,α-Trifluoro-p-tolualdehyde; 4-(Trifluoromethyl)benzaldehyde; p-(Trifluoromethyl)benzaldehyde; 4-Trifluoromethylbenzaldehyde; Benzaldehyde, 4-(trifluoromethyl)-; α,α,α-Trifluoro-4-methylbenzaldehyde; p-Trifluoromethylbenzaldehyde; TFMBA
EINECS	207-250-1

Quality Control

Our 4-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.