Description

2-Hydroxy-4-(Trifluoromethyl)Aniline is a versatile aromatic amine derivative characterized by the presence of both a hydroxyl and a trifluoromethyl group on the aniline ring. This unique molecular structure makes it a valuable high-purity intermediate for synthesizing advanced functional materials and active pharmaceutical ingredients. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Dye and Pigment Manufacturing: Serves as a precursor for developing specialized azo dyes and organic pigments with unique color fastness and spectral properties.
• Liquid Crystal & OLED Materials: An important intermediate in the synthesis of fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Additives: Can be incorporated into polymer chains to create materials with specific surface properties, UV stability, or chemical resistance.
• Research & Development: Employed in academic and industrial labs for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	2-Hydroxy-4-(Trifluoromethyl)Aniline
CAS No.	454-82-0
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)phenol; 5-(Trifluoromethyl)-2-aminophenol; 4-(Trifluoromethyl)-2-aminophenol; 2-Hydroxy-4-trifluoromethylaniline; 2-Amino-α,α,α-trifluoro-p-cresol; 5-Amino-2-hydroxybenzotrifluoride; 2-Amino-5-trifluoromethylphenol; 4-Trifluoromethyl-2-hydroxyaniline
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-(Trifluoromethyl)Aniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP and ISO 9001 standards to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.