Description

2-Amino-Alpha,Alpha,α-Trifluoro-p-Cresol is a specialized fluorinated aromatic amine derivative, serving as a critical building block in advanced chemical synthesis. Its unique trifluoromethyl and amino-adjacent phenolic structure makes it a valuable intermediate for introducing both fluorine and reactive amine functionality into target molecules. This compound is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients with enhanced properties. Our supply ensures consistent high purity and reliable availability for demanding industrial applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the production of fluorinated components for high-performance liquid crystal displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Intermediate for electron-transport or host materials in OLED device fabrication.
• Dye and Pigment Manufacturing: Serves as a fluorinated intermediate for creating specialty dyes with unique color fastness and stability.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance or low surface energy to advanced polymers.
• Chemical Research & Development: A versatile reagent for exploring new fluorination chemistry and creating novel compound libraries in medicinal chemistry.

Basic Information

Item	Details
Product Name	2-Amino-Alpha,Alpha,α-Trifluoro-p-Cresol
CAS No.	454-81-9
Molecular Formula	C8H6F3NO
Molecular Weight	177.13 g/mol
Synonyms	2-Amino-α,α,α-trifluoro-p-cresol; 2-Amino-4-(trifluoromethyl)phenol; 4-(Trifluoromethyl)-2-aminophenol; 2-Amino-4-hydroxybenzotrifluoride; 2-Amino-α,α,α-trifluoro-4-methylphenol; 2-Amino-4-trifluoromethylphenol; 2-Amino-4-(trifluoromethyl)phenol; Phenol, 2-amino-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-Alpha,Alpha,α-Trifluoro-p-Cresol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide detailed Certificates of Analysis (COA) that document identity, purity, and impurity profiles, typically determined by HPLC, GC, and NMR. Our quality commitment supports compliance with cGMP and ISO guidelines where applicable, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.