Description

2-Bromo-5-(Trifluoromethyl)Aniline is a versatile halogenated aniline derivative, distinguished by its bromine and trifluoromethyl substituents which confer unique reactivity and physicochemical properties. This compound is a critical building block in advanced organic synthesis, enabling the construction of complex molecules with tailored functionalities. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a core building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science: Used in the research and production of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Dye and Pigment Manufacturing: Functions as an intermediate in the creation of specialized dyes and pigments for high-performance applications.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Chemical Research: Employed in academic and industrial laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Aniline
CAS No.	454-79-5
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-Bromo-5-(trifluoromethyl)benzenamine; 2-Bromo-alpha,alpha,α-trifluoro-p-toluidine; 5-Amino-2-bromobenzotrifluoride; Benzenamine, 2-bromo-5-(trifluoromethyl)-; 2-Bromo-5-trifluoromethylaniline; 2-Bromo-5-trifluoromethylphenylamine; 2-Bromo-α,α,α-trifluoro-p-toluidine; p-Amino-2-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(Trifluoromethyl)Aniline undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.