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5-Fluoro-2-Methylphenol CAS NO 452-85-7


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CAS No.:452-85-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Fluoro-2-Methylphenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a methyl group on the phenol ring, makes it a valuable intermediate for creating more complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and stability.
  • Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and optical devices.
  • Polymer Modification: Employed to introduce fluorine-containing phenolic groups into polymer chains to alter thermal stability, chemical resistance, or surface properties.
  • Organic Synthesis Building Block: Utilized in various coupling reactions, etherifications, and as a protecting group precursor in complex multi-step syntheses.
  • Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments.

Basic Information

Product Name 5-Fluoro-2-Methylphenol
CAS No. 452-85-7
Molecular Formula C7H7FO
Molecular Weight 126.13 g/mol
Synonyms 2-Methyl-5-fluorophenol; 5-Fluoro-o-cresol; 5-Fluoro-2-cresol; 2-Hydroxy-4-fluorotoluene; 4-Fluoro-2-hydroxytoluene; 5-Fluoro-2-methyl-1-hydroxybenzene; 5-Fluorocresol; FMC
EINECS 207-207-5

Quality Control

Our 5-Fluoro-2-Methylphenol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 32 - 36 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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